Microbiome labs MegaPre™
Microbiome labs MegaPre™ is the first Precision Prebiotic™ supplement made up of clinically-tested, non-digestible oligosaccharides that can increase microbial diversity and selectively feed beneficial bacteria like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria.
MegaPre™ REINFORCES the beneficial microbial changes created by MegaSporeBiotic™ to promote a strong and diverse microbiome.
- Diversify the microbiome
- Support keystone species
- Support immunity
Microbiome labs MegaPre™ – Cutting-edge Precision Prebiotic™
MegaPre™ is a cutting-edge Precision Prebiotic™ supplement made up of clinically-tested, non-digestible oligosaccharides that can increase microbial diversity and selectively feed beneﬁcial, keystone bacteria like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacteria.
Prebiotics are non-digestible ﬁbers that feed the bacteria living in your gut. However, most prebiotics on the market can feed both harmful and beneﬁcial gut bacteria, which can exacerbate digestive issues. Keystone bacteria like bacterium Faecalibacterium prausnitzii, Akkermansia muciniphila, and Biﬁdobacteria are very important for human health, but their populations can be easily diminished by antibiotics, stress, diet, glyphosate, and other environmental toxins.
A. muciniphila plays an important role in metabolism and has been shown to promote fat loss. Low levels of A. muciniphila have been associated with obesity, diabetes, liver disease, cardiometabolic diseases, and low-grade inflammation.**
F. prausnitzii can increase the production of butyrate, a short-chain fatty acid that can relieve intestinal inflammation. Low levels of F. prausnitzii have been associated with irritable bowel syndrome, inflammatory bowel diseases (IBD) like Crohn’s disease and ulcerative colitis, celiac disease, and chronic constipation.**
Bifidobacteria can also increase butyrate production and promote lean body mass. Low levels of of Bifidobacteria have been associated with obesity, diabetes, celiac disease, allergic asthma, dermatitis, IBD, chronic fatigue syndrome, and psoriasis.**
**Increasing populations of these protective bacteria is an integral part of reinforcing a healthy gut microbiome. Studies have shown that a more diverse gut microbiome is associated with a stronger immune system and a decreased risk for chronic illness.
MegaPre + Immunity
Research shows that the ingredients in MegaPre™ can help support a strong immune system through the production of short-chain fatty acids (SCFAs), which can subsequently stimulate intestinal cells to produce a protective compound known as β-defensin that can help to keep the gut microbiome in balance.
One study found that consuming Livaux® gold kiwifruit concentrate, found in MegaSporeBiotic™, could modulate the immune system by increasing the production of T-cells and immunoglobulins, such as IgG, which can help support a balanced gut microbiome.
Another study conducted on the effects of B-GOS on immune function in elderly adults found that the lactose-derived B-GOS significantly increased phagocytosis and natural killer cell activity, two components that are essential for a strong immune system.
The three fundamental aspects of gut health include: the microbial population, physical structures, and regulatory immune function. A healthy gut microbiome is multi-faceted and relies heavily upon all 3 of these factors, like a three-legged stool.
For this reason, therapies that only address one of these facets do not typically provide total restoration of a dysfunctional GI tract. The Microbiome Labs Total Gut Restoration system was uniquely designed to target all 3 of these areas, providing healthcare professionals with highly effective tools in the battle against chronic disease
Aren’t all prebiotics the same?
Prebiotics are essentially dietary fibers that cannot be digested or absorbed by the human digestive tract but instead feed the bacteria living in your gut. The problem is that most prebiotics on the market are not selective.
This means that they can feed both harmful and beneficial gut bacteria, which can often exacerbate digestive issues.MegaPre™ contains medium-chain carbohydrates, known as oligosaccharides, that cannot be digested by humans but instead target keystone species known as secondary degraders.
Primary degraders feed on the bulkier fibers like cellulose, resistant starches, and inulin and then convert them into intermediate products like acetate, lactate, and oligosaccharides that can then feed the butyrate-producing secondary degraders.
These complex fibers are important because they can feed beneficial bacteria, but they can also be utilized byharmful bacteria. For this reason, we decided to skip the first step and provide the gut microbiome with the intermediate byproducts that it needs to produce beneficial short-chain fatty acids (SCFAs) like butyrate.
The oligosaccharides used in MegaPre™ have been clinically shown to significantly increase keystone species like:
- Akkermansia muciniphila
- Faecalibacterium prausnitzii
All of which are very important for a healthy metabolism, intestinal barrier function, and body composition.
Livaux® FOS increases F. prausnitzii by 100% in 4 weeks
- B-GOS increases Bifidobacteria by 67% in 1 week
- PreticX® XOS increases Bifidobacteria by 21% and significantly increases A. muciniphila in 4 weeks
- MegaPre™ was designed to specifically reinforce these keystone strains without feeding the dysbiotic flora in the gut.
MegaPre™ contains a proprietary blend of functional fibers that specifically feed these keystone bacteria. This unique blend is made up of clinically-tested-and-published, non-digestible oligosaccharides, derived from non-GMO green and gold kiwi fruit, non-GMO corn cob, and rBST-free cow’s milk.
|Non-GMO green and gold kiwifruit||Fructooligosaccharides|
|Non-GMO corn cob||Xylooligosaccharides|
|rBST-free cow’s milk||Galactooligosaccharides|
Increasing populations of these protective keystone bacteria like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Bifidobacterium species is an integral part of reinforcing a healthy gut microbiome.*
The findings of the oligosaccharide studies are quite impressive:
- FOS increased populations of A. mucin by 8,000% in 5 weeks
- FOS increased populations of F. prau by 100% in 4 weeks
- GOS increased populations of Bifido by 10% in 6 weeks
- XOS increased populations of Bifido by 9% in 8 weeks
Increasing populations of these protective bacteria is an integral part of reinforcing a healthy gut microbiome.
Nourish the powerful ecosystem in your gut with MegaPre™ today!
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.