MegaSporeBiotic™ SPORES ONLY by Microbiome Labs – 60 Capsules

Original price was: $74.07.Current price is: $66.59.

We are the best priced stockist of MegaSporeBiotic™ in the UK and Europe.

THIS IS THE MegaSporeBiotic™ SPORES ONLY FORMULA.

MegaSporeBiotic™ SPORES ONLY is a 100% spore-based, broad-spectrum probiotic shown to maintain healthy gut barrier function. This unique all-spore formula effectively RECONDITIONS the gut by promoting microbial diversity and maintaining key health-promoting, commensal gut bacteria. MegaSporeBiotic™ boasts a 5-year shelf-life, does not require refrigeration, and maintains a healthy gut microbiome.

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MegaSporeBiotic Spore Based Probiotic and Antioxidant 60 Capsules Bottle on Table
MegaSporeBiotic Spore Based Probiotic Logo

MegaSporeBiotic™: An Overview

The 1st probiotic to PROTECT its human host.

MegaSporeBiotic is a probiotic blend of 4 Bacillus spores that have been clinically shown to maintain healthy gut barrier function and overall immunity. The bi-phasic life cycle of the Bacillus spores allows them to remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract.

Once inside the large intestine, these dormant spores can change into their active, vegetative forms and begin colonizing in the gut. This unique probiotic blend aims to RECONDITION the gut instead of reseeding with probiotic strains that cannot survive digestion or colonize the gut. MegaSporeBiotic has quickly become a household favorite among health practitioners and consumers alike.

Among non-communicable diseases, intestinal permeability (metabolic endotoxemia) is the #1 cause of morbidity and mortality worldwide.

Intestinal permeability is present in most chronic diseases and is believed to be a major driver of many conditions.

MegaSporeBiotic is clinically shown to reduce intestinal permeability by 60%, when compared to the placebo control group, in just 30 days without any additional interventions.

Reduce LPS Translocation

Lipopolysaccharides, also known commonly as LPS are bacterial toxins that can health issues if they reach the bloodstream, such as Fatigue, Poor Memory and Depression.

Normally housed safely in the gut, lipopolysaccharides can enter the blood if you have an infection, “leaky gut”, or eat too many fatty foods.

Reduce Systemic Inflammation

By reducing Lipopolysaccharides translocation, MegaSporeBiotic helps to inhibit LPS from accumulating in the brain, where it can damage neurons and increase inflammation.

This helps to reduce inflammation on a systemic level, supporting your body’s healthy inflammatory response and healthy triglyceride balance.

Repair Leaky Gut

Some studies suggest that leaky gut plays a pivotal, and perhaps even causal, role in the development of many chronic diseases by triggering low-grade systemic inflammation.

MegaSporeBiotic™ has been shown to heal leaky gut by closing tight junctions between colonocytes, increasing the thickness of intestinal mucosa, and supporting the body’s natural defense against infections.

Buy MegaSporeBiotic™ from Synergistics Europe

Dosing Instructions:

  • Start with 1/2 capsule or 1 full capsule with food and slowly increase to 2 capsules per day using the following protocol.
  • For Week 1, 1 capsule every other day.
  • For Week 2, 1 capsule taken daily.
  • For Week 3+, 2 capsules taken every day.

Dosing Suggestions:

  • If 1 capsule every other day is too strong, try starting with 1/2 capsules or even 1/4 capsule in some cases. Possible symptoms may include abdominal cramping, loose stools, and changes in bowel movements.
  • Though these symptoms may be uncomfortable, they are a sign that the product is working!
  • Symptoms should resolve within 2-3 days.

Ingredients of MegaSporeBiotic™

MegaSporeBiotic™ SPORES ONLY FORMULA contains the following:

Bacillus Licheniformis

  • Produces proteases needed for protein digestion
  • Produces full spectrum of B vitamins

Bacillus Subtilis HU58™

  • Produces nattokinase and vitamin K2
  • Produces full spectrum of B vitamins

Bacillus Clausii

  • Supports immune function
  • Maintains efficacy during antibiotic treatment

Bacillus Coagulans

  • Produces L+ optical form of lactic acid
  • Supports immune function

Proprietary Blend 152mg:

5 Billion Spore Cells (5×109)
Bacillus subtilis, HU58™
Bacillus coagulans, SC-208
Bacillus calusii, SC-109
Bacillus licheniformis, SL-307

Other Ingredients:

Bulking Agent: Cellulose; Capsule Shell (cellulose, water); Active bacteria blend: see above)

Dosing Instructions

Start with 1/2 capsule or 1 full capsule with food and slowly increase to 2 capsules per day using the following protocol.

If 1 capsule every other day is too strong, try starting with 1/2 capsules or even 1/4 capsule in some cases. Possible symptoms may include abdominal cramping, loose stools, and changes in bowel movements. Though these symptoms may be uncomfortable, they are a sign that the product is working! Symptoms should resolve within 2-3 days.

Week 1: 1 capsule every other day

Week 2: 1 capsule daily

Week 3+: 2 capsules daily

Research

McFarlin BK, Henning AL, Carbajal KM.

Oral spore-based probiotic supplementation was associated with reduced incidence of post-prandial dietary endotoxin, triglycerides, and disease risk biomarkers. World J Gastrointest Pathophysiol. 2017 Aug 15; 8(3): 117–126.

Rhee KJ, Sethupathi P, Driks A, et al.

Role of commensal bacteria in development of gut-associated lymphoid tissue and preimmune antibody repertoire. J Immunol. 2004;172(2):1118-24.

De Punder K, Pruimboom L.

Stress induces endotoxemia and low-grade inflammation by increasing barrier permeability. Front Immunol. 2015;15(6):223.

Gong Y, Li H, Li Y.

Effects of Bacillus subtilis on epithelial tight junctions of mice with inflammatory bowel disease. J Interferon Cytokine Res. 2016;36(2).

Samanya M, Yamauchi K.

Histological alterations of intestinal villi in chickens fed dried Bacillus subtilis var. natto. Comp Biochem Physiol A Mol Integr Physiol. 2002;133(1):95-104.

Tam NKM, Uyen NQ, Hong HA, et al.

The Intestinal Life Cycle of Bacillus subtilis and Close Relatives. Journal of Bacteriology. 2006;188(7):2692-2700.

“Survival of Probiotics in Simulated Gastric Fluid.”

Food Science Center Report. Silliker Labs. RPN 16663. August 24, 2013.

Gibson GR, Rouzaud G, Brostoff J, et al.

An evaluation of probiotic effects in the human gut: microbial aspects. Final Technical report. FSA project ref G01022.

Lefevre M, Racedo SM, Ripert G, et al.

Probiotic strain Bacillus subtilis CU1 stimulates immune system of elderly during common infectious disease period: a randomized, double-blind placebo-controlled study. Immun Aging. 2015;12:24.

Serra CR, Earl AM, Barbosa TM, et al.

Sporulation during Growth in a Gut Isolate of Bacillus subtilis. J Bacteriol. 2014;196(23):4184-4196.

Hong HA, Khaneja R, Tam NMK, et al.

Bacillus subtilis isolated from the human gastrointestinal tract. Res Microbiol. 2009;160(2):134-143.

Mandel DR, Eichas K, Holmes J.

Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial. BMC Complement Altern Med. 2010;10:1.

Marseglia GL, Tosca M, Cirillo I, et al.

Efficacy of Bacillus clausii spores in the prevention of recurrent respiratory infections in children: a pilot study. Ther Clin Risk Manag. 2007;3(1):13-7.

Urdaci MC, Bressollier P, Pinchuk I, et al.

Bacillus clausii probiotic strains: antimicrobial and immunomodulatory activities. J Clin Gastroenterol. 2004;38(6 Suppl):S86-90.

Nista EC, Candelli M, Cremonini F, et al.

Bacillus clausii therapy to reduce side-effects of anti-Helicobacter pylori treatment: randomized, double-blind, placebo controlled trial. Aliment Pharmacol Ther. 2004 Nov;20(10):1181-8.

Gabrielli M, Lauritano EC, Scarpellini E, et al.

Bacillus clausii as a Treatment of Small Intestinal Bacterial Overgrowth. Am J Gastroenterol. 2009;104(5):1327-8.

Di Caro S, Tao H, Grillo A, et al.

Bacillus clausii effect on gene expression pattern in small bowel mucosa using DNA microarray analysis. Eur J Gastroenterol Hepatol. 2005;17(9):951-60.

Ciprandi G, Tosca MA, Milanese M, et al.

Cytokines evaluation in nasal lavage of allergic children after Bacillus clausii administration: A pilot study. Pediatr Allergy Immunol. 2004;15(2):148-51.

Casula G, Cutting SM.

Bacillus Probiotics: Spore Germination in the Gastrointestinal Tract. App Environ Microb. 2002;68(5):2344-2352.